Publications - Christophe Guilbert, PhD

• Guilbert C., Perahia D.

  A method to explore transition paths in macromolecules. Applications to phosphoglycerate kinase and hemoglobin, Computer Physics Communications, 91 (1995), 263-273.

• Guilbert, C., Pecorari, F., Perahia, D., & Mouawad, L.

  Low frequency motions in phosphoglycerate kinase. A normal mode analysis. Chem. Physics, 204, 327-336 (1996).

• Pecorari F., Guilbert C., Minard P., Michel Desmadril M., Jeannine M. YON

  Folding and functional complementation of engineered fragments from Yeast Phosphoglycerate Kinase. Biochemistry, 1996, 35.

• Benattar J.J., Nedyalkov M., Prost J., Tiss A., Verger R., Guilbert C.

  Insertion process of the protein single layer within a Newton black film. Physical Review Letters, 82 (1999), 5297.

• C. Guilbert, F. Ricard, J.C. Smith

  Dynamic Simulation of the Mouse Prion Protein. Biopolymers, 54 (6), 406-415 (2000).

• J. Sopkova, S. Fischer, C. Guilbert, A. Lewitt-Bentley, J.C. Smith

  Pathway for large-scale conformational change in Annexin V. Biochemistry, 39 (46), 14065-14074 (2000).

• B. Gilquin, Guilbert C, Perahia

  Unfolding of Hen Lysozyme by Molecular Dynamics Simulations at 300K. Proteins: Structure, Function, and Genetics, 41:58-74 (2000).

• Liliane Mouawad, David Perahia, Charles H. Robert, Christophe Guilbert

  New Insights into the Allosteric Mechanism of Human Hemoglobin from Molecular Dynamics Simulations. Biophys. J., 82:3224-3245 (2002).

• Chung J, Mujeeb A, Jiang Y, Guilbert C, Pendke M, Wu Y, James TL.

  A small molecule, Lys-Ala-7-amido-4-methylcoumarin, facilitates RNA dimer maturation of a stem-loop 1 transcript in vitro: structure-activity relationship of the activator. Biochemistry. 2008 Aug 5;47(31):8148-56.

• Guilbert C, James TL.

  Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets. J Chem Inf Model. 2008, Jun;48(6):1257-68.

• Pinto IG, Guilbert C, Ulyanov NB, Stearns J, James TL.

  Discovery of Ligands for a Novel Target, the Human Telomerase RNA, Based on Flexible-Target Virtual Screening and NMR. J Med Chem. (2008).

• Chen CK, Leung SS, Guilbert C, Jacobson MP, McKerrow JH, Podust LM

  Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole. PLoS Negl Trop Dis. 2010 Apr 6;4(4).

• Chung J, Ulyanov N, Guilbert C, Mujeeb A, James T.

  Binding Characteristics of Small Molecules that Mimic Nucleocapsid Protein-induced Maturation of Stem-loop-1 of HIV-1 RNA. Biochemistry. 2010.